‘Universal cancer vaccine’ breakthrough claimed by experts
Researchers have found a way to persuade the body’s immune system to attack tumours – and it is largely free from side effects
Ian Johnston Science Correspondent
Scientists have taken a “very positive step” towards creating a universal vaccine against cancer that makes the body’s immune system attack tumours as if they were a virus, experts have said.
Writing in Nature, an international team of researchers described how they had taken pieces of cancer’s genetic RNA code, put them into tiny nanoparticles of fat and then injected the mixture into the bloodstreams of three patients in the advanced stages of the disease.
The patients’ immune systems responded by producing “killer” T-cells designed to attack cancer.
The vaccine was also found to be effective in fighting “aggressively growing” tumours in mice, according to researchers, who were led by Professor Ugur Sahin from Johannes Gutenberg University in Germany.
“[Such] vaccines are fast and inexpensive to produce, and virtually any tumour antigen [a protein attacked by the immune system] can be encoded by RNA,” they wrote. …read more here
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