Deadly brain cancer stopped with new compound
Published 16 May 2018
By Ana Sandoiu
Fact checked by Tim Newman
Glioblastoma, one of the deadliest forms of brain cancer, may have found its nemesis. New research shows that the tumor, which is notoriously difficult to treat, can be halted by an experimental compound.
New research shows that an experimental compound can stop aggressive brain tumors from growing.
Glioblastoma is a particularly aggressive form of brain tumor, with a median survival rate of 10–12 months.
Part of the reason why glioblastomas are so deadly is that they arise from a type of brain cell called astrocytes.
These cells are shaped like a star, so when the tumors form they develop tentacles, which makes them difficult to remove surgically.
Additionally, the tumors advance rapidly. This is because astrocytes provide support to neurons and control the amount of blood that reaches them; so, when tumors form, they have access to a large number of blood vessels, helping cancerous cells to grow and spread very quickly.
Another reason that glioblastomas are so difficult to treat is their high rate of recurrence. This is partly due to a subpopulation of cells contained in the tumor called glioma stem cells (GSC) — a type of self-regenerating cancer stem cell that controls the growth of tumors.
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