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Alzheimer’s ‘Markers’ Don’t Doom You to Dementia

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Alzheimer’s ‘Markers’ Don’t Doom You to Dementia

By Dennis ThompsonHealthDay Reporter

TUESDAY, May 29, 2018 (HealthDay News) — Even if you discover that you have the first biological signs of Alzheimer’s, you are not doomed to develop the crippling dementia, a new study suggests.”Just because you have amyloid [proteins] in the brain doesn’t mean you’re going to get dementia tomorrow. It doesn’t mean you’re going to get dementia in five years,” said lead researcher Ron Brookmeyer. He’s a professor of biostatistics with UCLA’s Fielding School of Public Health.

“It could be many years, and it could be longer than your natural life expectancy,” Brookmeyer added.

For example, high levels of abnormal amyloid proteins in your brain or shrinkage of your brain each confer only a minimal risk of future dementia, a new statistical risk model indicates.

Further, a person’s dementia risk is even lower if the amyloid or shrinkage is detected at a more advanced age, the study authors noted.

On the other hand, a person’s risk does rise if early biological signs of Alzheimer’s start stacking up, the investigators found.

For instance, a 60-year-old man with high levels of amyloid protein has just a 23 percent chance of developing dementia in his lifetime, while a 60-year-old woman has a 31 percent risk, the researchers said.

Shrinking of specific brain regions confer similarly low lifetime dementia risks at age 60; about 23 percent for men and 30 percent for women.

But if men or women have both high amyloid levels and brain shrinkage at age 60, their dementia risk increases to 34 percent and 42 percent, respectively, according to the report.

People face the most risk if they have high amyloid levels, brain shrinkage and early signs of mild cognitive impairment, the researchers explained. This impairment usually crops up as memory loss…. more here: https://www.webmd.com/alzheimers/news/20180529/alzheimers-markers-dont-doom-you-to-dementia?src=RSS_PUBLIC#1


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